CJC-1295 reading list

Human measurements

Teichman and colleagues’ hormone and half-life study establishes the extended GH/IGF-1 response in healthy adults. Ionescu and Frohman’s pulsatility paper examines the raised basal GH level alongside preserved pulses. Sackmann-Sala and colleagues’ serum-protein study adds candidate biomarkers from 11 healthy young men.

The pulsatility paper gets my first pass for its revealing physiological detail, followed by the duration study. Together they explain why the molecule attracted attention before the question of clinical benefit was answered.

Chemistry, detection and safety

The rat and cell-free albumin-bioconjugate paper examines the chemistry behind DAC, while the GHRH-knockout mouse experiment asks about restoring a missing growth signal. The unknown-preparation identification paper opens the analytical branch of the record; later detection methods extend it.

For the clinical context, the GHRH-analog review covers related compounds. The IGF-1 cancer meta-analysis and GH sodium-retention study supply safety context at different levels of evidence. The FDA advisory materials, discontinued patient-trial record and WADA prohibited list carry their respective regulatory and development questions.

The complete reading list follows, including papers on other interventions and assay methods. Some full papers are paywalled; an abstract may leave details available only in the full study.